LICORbio™ | Applications

Applications_

LICORbio imaging systems are capable of a wide range of detection methods for multiple imaging applications. Our R&D team thoroughly tests each application to ensure consistent, high-quality data. This list is not exhaustive, and we support and add applications as we test them. View all applications or filter by imaging system using the buttons below. Each image leads to in-depth discussion, best practices, and resources for that application.

Gel ApplicationsSave time, reduce costs, and eliminate variables associated with membranes. With extremely sensitive two-color near-infrared detection, both Odyssey M imagers support a wide variety of gel-based applications with multiplexing capabilities.

EMSA/Gel Shift Assay

Easily study protein:DNA complexes and interactions.

Glycoprotein Staining

Detect and multiplex a variety of glycoprotein interactions.

Directly detect protein in polyacrylamide gel, without membrane transfer or blocking.

Nucleic Acid Gel Imaging

Label, visualize, and analyze in-gel DNA or RNA abundance.

Fluorescent Gel Staining

Quickly assess protein purity and detect degradation products.

Membrane ApplicationsLICORbio has continued to advance these essential assays since its release of the original Odyssey Imaging System in 2001. The Odyssey M employs industry-leading visible and near-infrared (NIR) fluorescent detection to provide the most consistent, reliable Western blot results possible.

Quantitative Western Blots

Multiplex, detect, and precisely quantify changes in target protein expression.

Chemiluminescent Western Blots

Capture digital images of enzymatic reactions to detect and visualize protein abundance.

Gene Knockdown and Knockout

Analyze genetic function and identify targets for potential therapeutic applications.

Rapidly assess protein abundance or modification state in many samples at once.

Multi-Well Plate ApplicationsLICORbio has expanded its offering of digital detection methods to include green fluorescent protein (GFP) and the novel In-Cell Western™ Assay. Such precise and replicable cell-based assays are the next iteration of quantitative protein analysis.

Easily detect and quantify target proteins, peptides, and antibodies using small samples and plate-based detection.

In-Cell Western™ Assay

Quantify in situ cell proteins to assess infectivity, neutralization, and signaling in many samples.

On-Cell Western Assay

Quantify fixed-cell surface proteins to evaluate mutations, therapeutics, and expression.

Protein Estimation Assays

Save time and minimize loading error with Bradford, Lowry, and BCA assays.

Accurately determine the level and impact of target gene knockdown.

FLUORESCENT PROTEINS

Label, quantify, and visualize protein expression, protein localization, and cells, tissues, organs, and whole organisms.

Slide ApplicationsWith up to 5 um resolution, the Odyssey M can examine cross-sections of ex vivo tissue to determine the presence or absence of disease, or to assess the efficacy, specificity, toxicity, localization, and biodistribution of a therapeutic.

Tissue Section Imaging

Perform macroscopic imaging of several tissue section slides simultaneously.

Rapidly assess protein abundance or modification state in many samples at once.

Whole Slide Imaging (WSI)

Quickly screen slides of interest to visualize biological processes, identify targets, and develop potential therapeutics.

FLUORESCENT PROTEINS

Label, quantify, and visualize protein expression, protein localization, and cells, tissues, organs, and whole organisms.

In vivo Applications

Therapeutic Delivery

Observe and characterize therapeutic delivery, biodistribution, and target specificity in live animals.

Therapeutic Response

Measure and track molecular mechanisms behind the activity of and response to your therapeutic.

FLUORESCENT PROTEINS

Label, quantify, and visualize protein expression, protein localization, and cells, tissues, organs, and whole organisms.